The Genetics of Cancer

Anne Li                                1/1/17   Cancer is a genetic disease—that is, cancer is caused by certain changes to genes that control the way our cells function, especially how they grow and divide. These changes include mutations in the DNA that makes up…...

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Paying for Clinical Trials

Anne Li                               1/1/17   As you think about taking part in a clinical trial, you will face the issue of how to cover the costs of care. There are two types of costs associated with…...

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No Safe Level of Smoking: Even low-intensity smokers are at increased risk of earlier death

Anne Li                              1/1/17   People who consistently smoked an average of less than one cigarette per day over their lifetimes had a 64 percent higher risk of earlier death than never smokers, and those who smoked…...

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Cellular Immunotherapy Targets a Common Human Cancer Mutation

Anne Li                                         1/1/17   In a study of an immune therapy for colorectal cancer that involved a single patient, a team of researchers at the National Cancer Institute (NCI) identified…...

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New Mouse Model Closely Mimics Most Common Leukemia in Infants

Anne Li                              1/1/17   Researchers have created a long-sought-after mouse model for the most common form of infant leukemia, an aggressive form of acute lymphoblastic leukemia (ALL) for which prognosis is poor. The model closely mimics…...

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Early-phase trial demonstrates shrinkage in pediatric neural tumors

Anne Li                                 1/1/17   In an early-phase clinical trial of a new oral drug, selumetinib, children with the common genetic disorder neurofibromatosis type 1 (NF1) and plexiform neurofibromas, tumors of the peripheral nerves, tolerated…...

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For Some Breast Cancer Survivors, Drug May Reduce Treatment-Related Joint Pain

Anne Li                                                1/1/17   A drug most commonly used to treat depression may also reduce joint pain in some women being treated for early-stage breast cancer, according…...

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‘Broken switch’ inside cancer cells could help them spread

Anne Li                                    1/1/17   Scientists in London have discovered a possible way that some cancer cells invade their surroundings and escape a tumour. If confirmed in patients, the findings could shed light on…...

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Large genetic analysis of oesophageal cancer could lead to better clinical trials

Anne Li                       1/1/17   The two main types of oesophageal, or food pipe cancer, display distinct genetic characteristics and should be studied separately in clinical trials, according to a large US study. The analysis from The Cancer Genome Atlas (TCGA) Research Network…...

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New Year honours for Cancer Research UK experts

Anne Li                              1/1/17   The New Year honours list includes three Cancer Research UK experts who are being recognised for their service to science. Michael Pragnell is Cancer Research UK’s previous chairman while Professor Jack Cuzick is a…...

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